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Chromosome 12 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 12 spans about 133 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 12 likely contains between 1,000 and 1,300 genes. It also contains the Homeobox C gene cluster. == Genes == The following are some of the genes located on chromosome 12: * ACVRL1: activin A receptor type II-like 1f * APOLD1: apolipoprotein L domain containing 1 * ATG101: Autophagy-related protein 101 * CBX5: chromobox homolog 5 * COL2A1: collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) * HPD: 4-hydroxyphenylpyruvate dioxygenase * KCNA1: potassium voltage-gated channel subfamily A member 1 at 12p13.32 * KERA: keratocan * KRAS: V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog * LRRK2: leucine-rich repeat kinase 2 * MMAB: methylmalonic aciduria (cobalamin deficiency) cblB type * MYO1A: myosin IA * NANOG: NK-2 type homeodomain gene * PAH: phenylalanine hydroxylase * PPP1R12A: protein phosphatase 1, regulatory (inhibitor) subungfdit 12A * PTPN11: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Chromosome 12 (human)」の詳細全文を読む スポンサード リンク
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